Vitamin D Levels and Vitamin D Receptor (VDR) Gene Polymorphisms in Inactive Hepatitis B Virus Carriers | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2021]

Author(s):

1. Suleyman Albas: Department of Family Medicine, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

2. Esra Meltem Koc: Department of Family Medicine, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

3. Salih Atakan Nemli: Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

4. Tuna Demirdal: Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

5. Mustafa Soyoz: Department of Medical Biology, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

6. Saliha Aksun: Department of Medical Biochemistry, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir,Turkey

7. Melih Kaan Sozmen: Department of Public Health, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

8. Candeger Avsar: Department of Medical Biochemistry, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir,Turkey

9. Burcu Cerci Gurbuz: Department of Medical Biology, Faculty of Medicine, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey

Abstract:

Objective: To evaluate the vitamin D receptor (VDR) gene polymorphisms and vitamin D levels in inactive hepatitis B virus (HBV) carriers. Study Design: A cross-sectional analytical study. Place and Duration of Study: From March to September 2017 at the Izmir Katip Celebi University (0KCU) Ataturk Training and Research Hospital, Izmir, Turkey. Methodology: Eighty-six inactive hepatitis B carriers and 86 control individuals were included in the study. Individuals with diseases or under medication that could a ect vitamin D levels were excluded from the studyS.erum vitamin D concentration of >30 ng/mL was considered as su cient, between 20-30 ng/mL as insu cient, 0.05). Conclusion: Vitamin D de ciency is highly prevalent both among control population as well as in chronic hepatitis patients.

Page(s): 393-398

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 31, Issue: 4, Year: 2021

Keywords:

Vitamin D , Polymorphism , Vitamin D receptor VDR , Inactive HBV carrier

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