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Talipes equinovarus or Clubfoot: A review of study approaches, management and trends in Pakistan
Author(s):
1. Khadija Murtaza: Human Genetics Program, Department of Zoology,Faculty of Biological Sciences, Quaid-i-Azam University,Islamabad, Pakistan.
2. Zahra Saleem: Human Genetics Program, Department of Zoology, Faculty of Biological Sciences, Quaid-i-Azam University,Islamabad,Pakistan
3. Sajid Malik: Human Genetics Program, Department of Zoology, Faculty of Biological Sciences, Quaid-i-Azam University,Islamabad,Pakistan
Abstract:
This paper aims to assess the status of scientific literature on talipes equinovarus (TEV) published from Pakistan, to get an insight into the trend in knowledge over the years, and to highlight study gaps in this area. A detailed review of published literature was conducted from November 2019 to January 2020. 'Talipes/ congenital talipes', 'clubfoot/congenital clubfoot', 'talipes equinovarus /congenital talipes equinovarus' AND 'Pakistan' were used as key terms. Different search engines, PubMed, PakMediNet, ScienceDirect, Embase and Google Scholar were utilized to retrieve articles. A total of 63 articles were retrieved. The hotspot of TEV research in Pakistan has been its treatment and management. Over the years, treatment trend has shifted from operative to conservative; Ponseti method is predominantly employed. Hospitalbased studies focusing on pediatric patients are common while population-based studies are devoid. In majority of cohorts, there is preponderance of male patients, idiopathic and unilateral cases. There is, however, scarcity of basic research on the prevalence, etiology, risk factors, clinical heterogeneity, associated anomalies, genetics, and molecular diagnostics of TEV. In conclusion, prudent scientific evidence is required for any policy-making and relevant public health action. Hence, large scale population-based studies are required for a broader overview and understanding the clinical spectrum of TEV.
Page(s): 1414-1420
DOI: DOI not available
Published: Journal: Pakistan Journal of Medical Sciences, Volume: 36, Issue: 6, Year: 2020
Keywords:
Congenital talipes equinovarus , Foot anomaly , Ponseti method , idiopathic clubfoot
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