A Case of Neuromyelitis Optica with Systemic Lupus Erythematosus | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2022]

Author(s):

1. Waleed Shahzad: Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

2. Haris Majid Rajput: Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

3. Muhammad Hassan: Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

4. Tehmina Inayat: Department of Medicine, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

5. Mazhar Badshah: Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

Abstract:

Neuromyelitis Optica (NMO) is a rare idiopathic autoimmune demyelinating disease of the central nervous system (CNS) having a relapsing course. It consists of optic neuritis, longitudinally extensive transverse myelitis (LETM) which involves 3 or more neighbouring portions of the spine and positive serology for anti-NMO IgG antibodies.NMO is often misdiagnosed as multiple sclerosis (MS). Limited literature about NMO and its association with other systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) is available so far. Here, we present a 21-year girl, previously diagnosed case of SLE seven years back, who su ered attacks of transverse myelitis. She had seropositivity for anti-aquaporin-4 (anti-AQP4) receptor antibody. An accurate clinical diagnosis is important to initiate timely immunosuppressive therapy to prevent disability.

Page(s): 1498-1500

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 32, Issue: 11, Year: 2022

Keywords:

Systemic lupus erythematosus , Neuromyelitis optica , Transverse myelitis

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