[1] Abadie C,Lalande J,Tcherkez G .2022 .Exact mass GC-MS analysis: Protocol, database, advantages and application to plant metabolic profiling. Plant Cell Environ, 45 : 3171-3183.
[2] Akagić A,Vranac A,Gaši F,Drkenda P,Spaho N,Oručević Žuljević S,Kurtović M,Musić O,Murtić S,Hudina M .2019 .polyphenols profile of commercial and traditional apple cultivars for processing. Acta Agric. Slov, 113(2) : 239-250.
[3] Akši´c MF,Zagorac DD,Tosti U,Meland T,M, T .2022 .Analysis of Apple Fruit (Malus domestica Borkh.) Quality Attributes Obtained from Organic and Integrated Production Systems. , 14 : 5300.
[4] Argenta LC,do Amarante CVT,de Freitas ST,Brancher TL,Nesi CN,Mattheis JP .2022 .Fruit quality of 'Gala' and 'Fuji' apples cultivated under different environmental conditions. Sci Hort, 303 : 111195.
[5] Bechynska K,Sedlak J,Uttl L,Kosek V,Vackova P,Kocourek V,Hajslova J .2024 .Metabolomics on apple (Malus domestica) cuticle-search for authenticity markers. Foods, 13 : 1308.
[6] Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD .2018 .HSI2/VAL1 silences AGL15 to regulate the developmental transition from seed maturation to vegetative growth in Arabidopsis. Plant Cell, 30(3) : 600-619.
[7] Chen X,Avia K,Forler A,Remoué C,Venon A,Rousselet A,Lucas G,Kwarteng AO,Rover R,Le Guilloux M,Belcram H,Combes V,Corti H,Olverà-Vazquez S,Falque M,Alins G,Kirisits T,Ursu TM,Roman A,Cornille A .2023 .Ecological and evolutionary drivers of phenotypic and genetic variation in the European crabapple [Malus sylvestris (L.) Mill.], a wild relative of the cultivated apple. Ann Bot, 131(6) : 1025-1037.
[8] Dhyani P,Bahukhandi A,Rawat S,Bhatt ID,Rawal RS .2018 .Diversity of bioactive compounds and antioxidant activity in Delicious group of apple in Western Himalaya. J. Food Sci. Tech, 55(7) : 2587-2599.
[9] Fiehn O .2016 .Metabolomics by Gas Chromatography-Mass Spectrometry: the combination of targeted and untargeted profiling. Curr Protoc Mol Biol, 114(30) : 1.
[10] Gao H,Liu P,Dou T,He W,Yang Q,Bi F,Li C,Hu C,Yi G,Deng G,Sheng O,Dong T .2025 .Ripening-stage variations in small metabolites across six banana cultivars: A metabolomic perspective. Food Chem, 143 : 143658.
[11] Geană EI,Ciucure CT,Ionete RE,Ciocârlan A,Aricu A,Ficai A,Andronescu E .2021 .Profiling of phenolic compounds and triterpene acids of twelve apple (Malus domestica Borkh.) cultivars. , 10(2) : 267.
[12] He S,Sun G,Geng X,Wenfang G,Panghong D,Yinhua J,Weijun S,Zhaoe P,Junduo W,Liyuan W,Songhua X,Baujun C,Shufang C,Chunyuan Y,Zongming X,Feng W,Jie S,Guoyong F,Zhen P,Daowu H,Liru W,Baoyin P,Xiongming D .2021 .The genomic basis of geographic differentiation and fiber improvement in cultivated cotton. Nat Genet, 53 : 916-924.
[13] Jia M,Du P,Ding N,Zhang Q,Xing S,Wei L,Zhao Y,Mao W,Li J,Li B,Jia W .2017 .Two FERONIA-like receptor kinases regulate apple fruit ripening by modulating ethylene production. Front. Plant Sci, 01406 : 1406.
[14] Joshi S,Awan H,Paul P,Tian R,Perry SE .2022 .Revisiting AGAMOUS-LIKE15, a key somatic embryogenesis regulator, using nextgeneration sequencing analysis in Arabidopsis. Int. J. Mol. Sci, 23(23) : 15082.
[15] Kagaya H,Ito N,Shibuya T,Komori S,Kato K,Kanayama Y .2020 .Characterization of flowering locus c homologs in apple as a model for fruit trees. Int. J. Mol. Sci, 21(12) : 4562.
[16] Karagiannis E,Michailidis M,Tanou G,Scossa F,Sarrou E,Stamatakis G,Samiotaki M,Molassiotis Fernie AR,A Fernie AR .2020 .Decoding altitude-activated regulatory mechanisms occurring during apple peel ripening. Hortic. Res, 7(1) : 40.
[17] Kumar G,Arya P,Gupta K,Randhawa V,Acharya V,Singh AK .2016 .Comparative phylogenetic analysis and transcriptional profiling of MADS-box gene family identified DAM and FLC-like genes in apple (Malus × domestica). Sci. Rep, 6 : 20695.
[18] Kumar P,Sethi S,Sharma RR,Singh S,Saha S,Sharma VK,Sharma SK,Varghes E .2019 .Influence of altitudinal variation on the physical and biochemical characteristics of apple (Malus domestica). Indian J. Agri. Sci, 89 : 86197-152.
[19] Kumar V,Kumar P,Bhargava B,Rohit S,Mohammad I,Rahul C .2023 .Transcriptomic and metabolomic reprogramming to explore the high-altitude adaptation of medicinal plants: A review. J. Plant Growth Reg, 42 : 7315-7329.
[20] Li W,Wang Y,Zhang Y,Wang R,Guo Z .2020 .Impacts of drought stress on the morphology, physiology, and sugar content of Lanzhou lily (Lilium davidii var. Acta Physiol. Plant, 42 : 127.
[21] Li Y,Sun H,Li J,Qin S,Yang W,Ma X,Qiao X,Yang B .2021 .Effects of genetic background and altitude on sugars, malic acid, and ascorbic acid in fruits of wild and cultivated apples (Malus sp. Foods, 10 : 2950.
[22] Li Q,Wang T,Xu C,Li M,Tian J,Wang Y,Zhang X,Xu X,Han Z,Wu T .2022 .MdMADS6 recruits histone deacetylase MdHDA19 to repress the expression of the carotenoid synthesis-related gene MdCCD1 during fruit ripening. Plants, 11(5) : 668.
[23] Liu W,Zheng L,Qi D .2020 .Variation in leaf traits at different altitudes reflects the adaptive strategy of plants to environmental changes. Ecol. Evol, 10(15) : 6519-8175.
[24] Locatelli G,Pio R,Bisi RB,De Souza FBMH,Viana MTR,Da Hora FD,De Castro EM,Zambon CR .2019 .Leaf anatomy of apple trees during seasonal periods under subtropical conditions. Hort. Sci, 54(11) : 1887-1895.
[25] McAtee PA,Richardson AC,Nieuwenhuizen NJ,Gunaseelan K,Hoong L,Chen X,Atkinson RG,Burdon JN,David KM,Schaffer RJ .2015 .The hybrid non-ethylene and ethylene ripening response in kiwifruit (Actinidia chinensis) is associated with differential regulation of MADS-box transcription factors. BMC Plant Biol, 15 : 97.
[26] Metusala D .1862 .An alternative simple method for preparing and preserving cross-section of leaves and roots in herbaceous plants: Case study in Orchidaceae. AIP Conf. Proc, : .
[27] Migicovsky Z,Gardner KM,Richards C,Thomas CC,Schwaninger HR,Fazio G,Zhong GY,Myles S .2021 .Genomic consequences of apple improvement. Hort. Res, 8(1) : 8.
[28] Monago-Maraña O,Afseth NK,Knutsen SH,Wubshet SG,Wold JP .2021 .Quantification of soluble solids and individual sugars in apples by Raman spectroscopy: A feasibility study. Postharvest Biol. Tech, 11 : 111620.
[29] Paudel BR,Dyer AG,Garcia JE,Shrestha M .2019 .The effect of elevational gradient on alpine gingers (Roscoea alpina and R. purpurea) in the Himalayas. PeerJ, 9 : 7503.
[30] Patocka J,Bhardwaj K,Klimova B,Nepovimova E,Wu Q,Landi M .2020 .Malus domestica: A review on nutritional features, chemical composition, traditional and medicinal value. Plants, 9 : 1408.
[31] Paul V,Sharma L,Pandey R,Meena RC .2017 .Manual of ICAR Sponsored Training Programme on “Physiological Techniques to Analyze the Impact of Climate Change on Crop Plants”. , : .
[32] Pfaffl MW .2001 .A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res, 29(9) : .
[33] Salem MA,Takuya Y,de Souza LP,Saleh A,Krzysztof B,Alisdair RF,Patrick G .2020 .An improved extraction method enables the comprehensive analysis of lipids, proteins, metabolites and phytohormones from a single sample of leaf tissue under water-deficit stress. The Plant J, 103 : 1111-1632.
[34] Sallato B,Bonomelli C,Martiz J .2016 .Differences in quality parameters and nutrient composition in Fukumoto oranges with and without creasing symptoms. J. Plant Nut, 1184 : 954-963.
[35] Seyednami N,Yukihiro N,Jashbir S,Kevin RM,Jifon JL,Jayaprakashab GK,Paul SB,Daniel L,Thomas A,Jonathan S,Timothy C,Wenjing G,Rhonda M,Bhimanagouda P,Xiaoning Q,Hisashi K .2023 .Genetic and geographical inputs that shape metabolomic and transcriptomic profiles of melon fruits. Sci. Hortic, 112337 : 112337.
[36] Shen C,Zhang Y,Li Q,Liu S,He F,An Y,Zhou Y,Liu C,Yin W,Xia X .2021 .PdGNC confers drought tolerance by mediating stomatal closure resulting from NO and H₂O₂ production via the direct regulation of PdHXK1 expression in Populus. , 230(5) : 1868-1882.
[37] Srednicka-Tober D,Baranski M,Kazimierczak R,Ponder A,Kopczynska K,Hallmann E .2020 .Selected antioxidants in organic vs. conventionally grown apple fruits. Appl. Sci. (Switzerland), 10(9) : 2997.
[38] Sun T,Junke Z,Qiang Z,Xingliang L,Minji L,Yuzhang Y,Jia Z,Qinping W,Beibei Z .2021 .Integrative physiological, transcriptome, and metabolome analysis reveals the effects of nitrogen sufficiency and deficiency conditions in apple leaves and roots. Environ. Exp. Bot, 104 : 104633.
[39] Tang X,Li J,Liu L,Jing H,Zuo W,Zeng Y .2022 .Transcriptome analysis provides insights into Potentilla bifurca adaptation to high altitude. Life, 12 : 1337.
[40] Théroux-Rancourt G,José CH,Klara V,De Berardinis F,Luijken N,Laura N,Tadeja S,Susanne S,Moritz S,Danny T .2023 .Analyzing anatomy over three dimensions unpacks the differences in mesophyll diffusive area between sun and shade Vitis vinifera leaves. AoB PLANTS, 15 : 1-13.
[41] Urrestarazu J,Muranty H,Denancé C,Leforestier D,Ravon E,Guyader A,Guisnel R,Feugey L,Aubourg S,Celton JM,Daccord N,Dondini L,Gregori R,Lateur M,Houben P,Ordidge M,Paprstein F,Sedlak J,Nybom H,Durel CE .01923 .Genome-wide association mapping of flowering and ripening periods in apple. Front. Plant Sci, 8 : .
[42] Wang R,Chen H,Liu X,Wang Z,Wen J,Zhang S .2019 .Plant phylogeny and growth form as drivers of the altitudinal variation in woody leaf vein traits. Front. Plant Sci, 01735 : 1735.
[43] Wishart DS .2018 .Metabolomics for investigating physiological and pathophysiological processes. Physiol Rev, 99 : 1819-1875.
[44] Xiang W,Guo Z,Han J,Gao Y,Gong X .2023 .The apple autophagy-related gene MdATG10 improves drought tolerance and water use efficiency in transgenic apple plants. Plant Physiol. Biochem, 108214 : 108214.
[45] Xu J,Jinjiao Y,Wenjie L,Qianying W,Caixia W,Junxing G,Dali G,Qingmei G,Fengwang M .2020 .Integrative analyses of widely targeted metabolic profiling and transcriptome data reveals molecular insight into metabolomic variations during apple (Malus domestica) fruit development and ripening. Int. J. Mol. Sci, 21 : 4797.
[46] Zhao Y,Wang C .2015 .Effect of calcium chloride in combination with salicylic acid on postharvest freshness of apples. Food Sci. Biotech, 24(3) : 1139-1146.