The effectiveness of different doses or types of vitamin D supplementation in H-VIpositive individuals in Lahore | [Pakistan Journal of Health Sciences • 2023]

Author(s):

1. Fatima Majeed: Department of Public Health, University of the Punjab, Lahore, Pakistan

2. Javeria Saleem: Department of Public Health, University of the Punjab, Lahore, Pakistan

3. Kifayat Ullah: Department of Public Health, University of the Punjab, Lahore, Pakistan

4. Shamsa Rafique: Department of Public Health, University of the Punjab, Lahore, Pakistan

5. Gul Mehar Javaid Bukhari: Department of Community Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan

6. Aimen Dilnawaz: University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom

7. Ali Tariq: Department of Public Health, University of the Punjab, Lahore, Pakistan

8. Ferheen Shahbaz: Department of Public Health, University of the Punjab, Lahore, Pakistan

Abstract:

The average lifespan of people suffering from HIV-AIDS is estimated to be 9 to 11 years, with Vitamin D deficiency as one of the most common phenomena among them. Anti-Retroviral Therapy (ART) could significantly enhance the quality of life of HIV-AIDS patients; however, it further decreases Vitamin D serum levels among them. Objectives: To evaluate the impact of vitamin D supplementation on immune function, viral load, and other health outcomes in HIVpositive individuals. Methods: This was a descriptive study conducted on a sample of 95 HIVdiagnosed patients aged 19 to 50 years in Punjab, Pakistan. Patients were selected from an AIDS control clinic and prescribed antiretroviral therapy. Baseline assessments were conducted using a structured evaluation questionnaire, and biochemical results were used to classify vitamin D de??ciency. Results: The study presents information on PCR viral load counts in HIV patients, including minimum (50), and maximum (750,000) values, mean (32,475) with standard deviation (155,343), 5% sheared mean (28), and the 95% confidence interval (17,802 to 47,148) for the average. Results showed that HIV-positive patients taking vitamin D supplementation had a lower mean rank (50.07) compared to those not taking supplements (57.00), with a difference of 275.5 in the sum of ranks between the two groups. Inferential statistics suggested that vitamin D plays a significant role in improving the prognosis of HIV patients taking ART, with a significance value of 0.0032. Conclusion: The present study concludes that Vitamin D supplementation has a signi??cant role in improving the life status of HIV patients.

Page(s): 43-48

DOI: 10.54393/pjhs.v4i04.673

Published: Journal: Pakistan Journal of Health Sciences, Volume: 4, Issue: 4, Year: 2023

Keywords:

Pakistan , HIV , Vitamin D , aids , Vitamin D3 , ART , 250HD

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