To Determine the Diagnostic Accuracy of CRP and WCC in Non-traumatic Acute Abdomen by Taking Ct Scan Findings as Gold Standard. | [Isra Medical Journal • 2018]

Author(s):

1. Shahzad Ahmed: The Royal Oldham Hospital, Oldham, UK

2. Ghulam Murtaza: The Royal Oldham Hospital, Oldham, UK

3. Rizwan Aziz: The Royal Bolton Hospital, Bolton, UK

4. Ishtiaq Ahmed: Al-Nafees Medical College & Hospital, Islamabad, Pakistan

Abstract:

OBJECTIVE: To determine the diagnostic accuracy of C - Reactive Protein (CRP) and White Cell Count (WCC) in non-traumatic acute abdomen pathologies by taking CT scan findings as gold standard. STUDY DESIGN: A retrospective analytic cross sectional study PLACE AND DURATION: At Pinder fields Hospital Mid Yorkshire NHS Trust, over a period of 6 months from 1st January 2014 to 31st June 2014. METHODOLOGY: All patients reporting to Emergency Department due to non-traumatic acute abdomen were included. Other than all basic demographic information, C- Reactive Proteins and White Cell Count within 24 hour of admission were recorded and its diagnostic value compared to the final diagnosis of all patients with CT scan. CRP > 5 mg/l and WCC 11 were taken as abnormal. RESULTS: A total of 396 patients were studied, with mean age 59 years and male to female ratio was 1:1.5. Positive CT showing acute abdomen pathologies were 74.24% and 25.86% were negative. Abnormal WCC and Positive CT scan were found in 154 patients with Specificity of WCC 72% and Sensitivity of WCC 52%. The Pearson Chi-Square showing p-value < 0.001, which is highly significant i.e. there is a trend that abnormal WCC is associated with positive CT scan. The specificity and sensitivity of positive CT scan findings were 84% and 89-91% when CRP levels were more than 50 with normal or abnormal WCC. This reaches up to 97% with raised WCC and 100% with normal WCC. CONCLUSION: C -reactive proteins more than 100 U/L has high diagnostic value and indication for CT scan or Surgery in diagnosing the exact cause of acute abdomen.

Page(s): 331-335

DOI: DOI not available

Published: Journal: Isra Medical Journal, Volume: 10, Issue: 6, Year: 2018

Keywords:

Keywords are not available for this article.

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