Pakistan Science Abstracts
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Synergistic effects of essential oils and antibiotics against Listeria monocytogenes
Author(s):
1. Farheen Zahid: Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan
2. Ayesha Khan: Department of Biological Sciences, International Islamic University, Islamabad, Pakistan
3. Mohammad Faisal: Institute of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan
4. Asma Latif: Animal Health Laboratories, Animal Sciences Institute, NARC, Islamabad, Pakistan
Abstract:
Listeria monocytogenes is a common pathogen that most readily forms biofilm and causes severe public health issue as with the consumption of contaminated products with high mortality when compared to other food-borne microbes. The characteristic feature of Listeria monocytogenesis formation of biofilms, which help them exist onboth biotic surfaces,particularly in the gastrointestinal tract and placenta during pregnancywhich take to sepsis as several cases has been reportedto date and on abiotic surfaces such as on medical devices, that pose a greater risk of antibiotic resistance and cross contamination and that shows a way to treatment failure. Thesebiofilms when combined with several factors cause drug resistance, which leads to poor diffusion of antibiotics, phenotypicand physiological changes in cells, quorum sensing, efflux pump and persisted cells conjugation and ATPbinding cassette transporter mechanisms. The use of naturally-derived products such as essential oils is empirical to overcome Listeria monocytogenesinfections. The eugenol, carvacrol,thymol and cinnamaldehy depresent in most essential oils showed bactericidal activity against Listeria monocytogenes. This work outlines the mode of action and synergistic effect of essential oils and antibiotic therapyagainst Listeria monocytogenes biofilms and how this approach can limit infections and prevent cross contamination at industrial scale.
Page(s): 390-390
DOI: DOI not available
Published: Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
essential oils , Listeria monocytogenes , antibiotics , biofilms , Synergistic effects
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