Acetylation percentage method for determination of acetylator status in human volunteers and tuberculous patients. | [Pakistan Journal of Pharmaceutical Sciences • 1995]

Author(s):

1. Abdul Sattar Sohrani: Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan

2. Bashir Ahmad: Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan

3. Khalid Hussain Janbaz: Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan

Abstract:

Acetylation percentage method described here is rapid and economical. A comparison has been made between plasma half life (t1/2), acetylation ratio and acetylation percentage methods for the determination of phenotyping. Isoniazid (INH) was selected as a test drug. In 120 healthy volunteers and 60 tuberculosis patients, acetylation percentage method has been found simple and reliable as compared to the other methods.

Page(s): 11-16

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 8, Issue: 1, Year: 1995

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