Spectrophotometric determination of Sulpiride in pure form and pharmaceutical preparations. | Proceedings of Pakistan Academy of Sciences 2005

Author(s)

Asrar A. Kazi Pakistan Council of Scientific and Industrial Research Laboratories Complex, Lahore, Pakistan

Tehseen Aman Pakistan Council of Scientific and Industrial Research Laboratories Complex, Lahore, Pakistan

Amina Mumtaz Pakistan Council of Scientific and Industrial Research Laboratories Complex, Lahore, Pakistan

Saba Ibrahim Department of Chemistry, Government College University, Lahore, Pakistan

Islamullah Khan Department of Chemistry, Government College University, Lahore, Pakistan

Abstract

Sulpiride reacts with chloranil to give a green coloured complex after heating for 100s at 100oC having maximum absorbance at 590nm. The reaction is selective for sulpiride with 0.01 mg/10 nil as visual limit of quantitation and provides a basis for a new spectrophotometric determination. The reaction obeys beer’s Law from 0.01 to 3.5 mg/10 ml of sulpiride and the relative standard deviation is 0.68 %. The quantitative assessment of tolerable amounts of other drugs not interfering has also been studied.

Publication Details

Page(s) 35-40

DOI DOI not available

Published Journal: Proceedings of Pakistan Academy of Sciences, Volume: 42, Issue: 1, Year: 2005

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