Abstract:
OBJECTIVE: To evaluate Vitamin D in Pulmonary tuberculosis and normal healthy adults. STUDY DESIGN: Case control study. PLACE AND DURATION: Department of Medicine, Isra University Hospital Hyderabad, from January 2013- June 2014. SUBJECTS & METHODS: A sample of 209 diagnosed pulmonary tuberculosis patients was selected through non-probability purposive sampling according to inclusion and exclusion criteria. After taking informed written consent from the participants, Vitamin D was measured by ARCHITECT I 1000 system for estimation of 25-OH- D3. . The data was recorded on a pre-structured proforma, and analyzed on SPSS version 21.0. The significant p-value was taken at = 0.05. RESULTS: The mean ±S.D serum level of 25-hydroxyvitamin D3 in cases and controls were 27.1±9.7 and 36.8±8.1 (ngdl-1) respectively (p=0.0001).The 25-hydroxyvitamin D3 levels as low as 6 ng/dl were observed in pulmonary tuberculosis subjects. The normal, insufficiency and deficiency of 25-hydroxyvitamin D3 were observed in 37(33%), 16 (14.2%) and 59 (52.6%) in cases respectively compared to controls as 57 (58.7%), 21(21.6%) and 19 (19.5%) respectively. CONCLUSION: Patients with pulmonary tuberculosis are significantly Vitamin D deficient. Vitamin D supplements may be prescribed, however further studies are warranted.
Page(s):
16-20
DOI:
DOI not available
Published:
Journal: Journal of Liaquat University of Medical and Health Sciences, Volume: 15, Issue: 1, Year: 2016