Abstract:
Background: A plant's activity towards biological properties is the first step to consider it for medicinal and therapeutic purposes. To evaluate the medicinal properties, we have determined the anti-bacterial and anti-fungal potential of Moringa oleifera L. (Benzoil tree). The focus was to obtain and isolate certain chemical substances that can neutralize the effect of common and pathogenic selected bacterial and fungal species collected from local hospitals of Khyber Pakhtunkhwa. Methods: A total of five fractions were selected i.e. crude methanolic extracts, n-hexane, chloroform, ethyl acetate and aqueous extracts were prepared and their activity checked against four bacterial strains including Streptococcus mutans, Staphylococcus aurous, MRSA (methicillin resistance Staphylococcus aurous) and Serratia marcescens; and four fungal strains i.e. Fusarium oxysporum, Aspergillus flavus, Polysphondylium pallidum and Alternaria alternata. Results: The highest anti-bacterial activity shown by crude methanolic extract fraction i.e. (48-38%) and the lowest activity was exhibited by aqueous extract (15-0%) against all the selected bacterial strains. Similarly, the highest anti-fungal activity indicated by crude methanolic extracts (60-45%) against the four selected fungal species and lowest activity shown by the aqueous fractions (26-0%). Reasonable activity was also exhibited by others fractions as well. Conclusion: The outcomes of our experiment strongly supports that Moringa oleifera has significant antibacterial and antifungal activities, so the plant is effective antibacterial and antifungal agent.
Page(s):
135-139
DOI:
DOI not available
Published:
Journal: Advancements in life sciences, Volume: 7, Issue: 3, Year: 2020
Keywords:
antibacterial
,
Antifungal
,
Moringa oleifera
,
Benzoil tree
,
Drum stick Tree