Abstract:
To observe and compare the intraocular pressure (IOP) lowering effect of trabeculectomy with topical application of mitomycin C, using two different concentrations, of 0.2mg/ml and 0.4mg/ml, in high risk glaucoma patients. Forty eyes of 26 patients of glaucoma, who were considered to be at high risk for failure because of their young age, previous ocular surgery like cataract extraction and trabeculectomy, inflammatory glaucoma, high myopia and prolonged anti-glaucoma medication, underwent trabeculectomy with topical application of 0.2mg/ml concentration of mitomycin C for three minutes. They were case matched with a group of same number of eyes of 27 high risk glaucoma patients who received 0.4mg/ml concentration of drug for same duration. The mean pre-operative IOP in the two groups was similar (29.63mmHg in group I and 30.43mmHg in group II). Twelve months after surgery, the mean preoperative IOP decreased from 29.63mmHg to a post-operative level of 16.15mmHg in group I, with a success rate of 85%, and from 30.43mmHg to 16.88mmHg in group II, with the success rate of 82.5%. This difference in success rate is not significant statistically (p
Page(s):
23-27
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Ophthalmology , Volume: 22, Issue: 1, Year: 2006