A retrospective analysis of Acute Lymphoblastic Leukemia incidence among hospitalized patients from Jan- 2017 to Sep-2021 | [Pure and Applied Biology • 2022]

Author(s):

1. Sajid Ali: Hayatabad Medical Complex Peshawar, Pakistan

2. Ayesha Sadia: Hematology KMU Peshawar, Pakistan

3. Abid Jameel: Hayatabad Medical Complex Peshawar, Pakistan

4. Sufyan: Hayatabad Medical Complex Peshawar, Pakistan

5. Shah Hussain: Hayatabad Medical Complex Peshawar, Pakistan

6. Shehryar Ahmad: Health Department Khyber-Pakhtunkhwa, Pakistan

Abstract:

Acute Lymphoblastic Leukemia (ALL) is heterogeneous group of genetically linked lymphoid neoplasm associated with increased incidence rate. This study was designed to determine the incidence of ALL in Khyber Pakhtunkhwa based on the age, gender and geographic distribution. A retrospective study was conducted by reviewing hospital record at Medical Oncology ward of Hayatabad Medical Complex Peshawar, Pakistan. A total of 161 patients were selected from January 2017 to September 2021 who met the criteria of ALL were included. The incidence was higher in children under ages under 23 years whereas the highest number of cases was reported from district DIR of Khyber Pakhtunkhwa province which is quite alarming. Male to female ratio was 1.27:1 respectively whereas male shows slightly predominance as compare to female. This study concludes increase incidence of ALL in children whereas increase frequency in District DIR population along with male predominance attract attention regarding further study to evaluate the possible etiologies behind increase incidence.

Page(s): 902-906

DOI: 10.19045/bspab.2022.110092

Published: Journal: Pure and Applied Biology, Volume: 11, Issue: 4, Year: 2022

Keywords:

Khyber Pakhtunkhwa , Acute lymphoblastic leukemia , Flow cytometry , Philadelphia , Bone marrow

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