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Ethnic-specific polymorphisms in breast cancer: advancing early diagnosis and personalized treatment in the Pashtun population of Khyber Pakhtunkhwa, Pakistan
Author(s):
1. Najeeb Ullah Khan: IBGE, The University of Agriculture, Peshawar, Pakistan
2. Iqbal Munir: IBGE, The University of Agriculture, Peshawar, Pakistan
Abstract:
Breast cancer poses a significant global health burden, with variations in genetic predisposition among different ethnic groups. Understanding ethnic-specific polymorphism associated with breast cancer risk is crucial for improving early diagnosis and prognosis. This study focuses on investigating gene polymorphisms related to breast cancer in the Pashtun population of Khyber Pakhtunkhwa, Pakistan. Through extensive research, we have established the significant association of various gene polymorphisms, including BRCA1&2, TP53, RANKL, OPG, IL-6, HER1, and HER2, with breast cancer risk in this particular ethnic group. The findings from this study offer valuable insights that can enhance early diagnosis and prognosis of breast cancer cases among the Pashtun population, facilitating the development of personalized treatment approaches for improved patient outcomes.
Page(s): 50-50
DOI: DOI not available
Published: Journal: Abstract Book on International Conference on Sustainable Agriculture and Food Security, August 27-31, 2023 , Volume: 0, Issue: 0, Year: 2023
Keywords:
Breast cancer , Early diagnosis , genetic polymorphism , personalized treatment
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