Abstract:
Ethy-2-oxo- ?1:9- octalin-l0-carboxylate (I) reacts with diethylamine hydrochloride and parfyrmaldehyde to yield Ethyl I methyl (N-diethylamino) -2-oxo-?1:9-octalin-10-carboxylate Its methiodide (II) on treatment with sodio-derivatives of Ethylacetoacet0e gave Ethyl-2-oxo-1-(3-keto-butyl-2-ethyl carboxylate)- ?1:9 (16), Ethy1-2-oxo-1-(3-ketobuty1-2 ethyl carboxylate) -?1:9-octalin-l0 carboxylate (16) was also prepared by the enamine method. The compound (16) on cyclization yields diethyl-2-oxo-2, 3, 4, 5, 6, 7, 8, 9, 10, 14-decandrophenanthrene-3: 4-dicarboxylate (2), which on hydrolysis and decarboxylation gave β-unsaturated ketone (3). A series of α -alkyated and acylated derivatives (5 and 7) have been prepared by the Stork et al. method. These have been hydrolysed and decarboxylated to the corresponding or αβ-unsaturated tricyclic ketones (6 and 8).
Page(s):
1-20
DOI:
DOI not available
Published:
Journal: Sindh University Research Journal, Volume: 13, Issue: , Year: 1981