Abstract:
Objective: The purpose of this study was to determine the prevalence and risk factors of newborn jaundice. Study Design: In this retrospective study, 3200 newborns with jaundice with bilirubin level >17 mg/dl were investigated. Place and Duration of Study: The newborn department of Ghaem Hospital of Mashhad, Iran during 2007-2017. Material and Methods: A self-administered questionnaire containing maternal information, neonatal profileand laboratory parameters was completed. Results: From the 14183 neonates referred to the study center over 10 years, 3200 were hospitalized for jaundice. The most common underlying diagnoses were: idiopathic (n=1754, 66.9%), ABO incompatibility (n=279,10.6%), G6PD deficiency (n=149, 6.0%), urinary tract infection (n=101, 3.9%), Rh incompatibility (n=80, 3.1%), sepsis (n=44,1.7%), polycythemia (n=44, 1.7%). The presence of pregnancy complications (25%), history of jaundice in a previous sibling (42.9%) and history of hospitalization (32.4%) were other predisposing factors in newborns admitted with jaundice. Conclusion: The major known causes of newborn jaundice were ABO incompatibility, G6PD deficiency, urinary tract infection, Rh incompatibility, polycythemia and hypothyroidism.
Page(s):
345-350
DOI:
DOI not available
Published:
Journal: Pakistan Paediatric Journal, Volume: 44, Issue: 4, Year: 2020
Keywords:
Risk Factors
,
jaundice
,
Causes
,
Newborns
,
therapy