The effects of Mefenamic acid on the osmotic fragility of Lacertilian Erythrocytes. | [Pakistan Journal of Pharmaceutical Sciences • 2005]

Author(s):

1. Mahmood Ahmad: Department of Physiology, University of Karachi, Karachi, Pakistan

2. Ruqaiya Hasan: Department of Physiology, University of Karachi, Karachi, Pakistan

3. Zulfiqar Ahmed: Department of Physiology, University of Karachi, Karachi, Pakistan

4. Anila Qureshi: Department of Physiology, New York Medical College, Westchester Hospital, Valhalla, New York, USA

5. Mansoor Ahmad: Department of Physiology, New York Medical College, Westchester Hospital, Valhalla, New York, USA

Abstract:

Osmotic fragility of red cells is increased by the use of mefenamic acid. The use of this analgesic induces hemolytic anemia. Study of osmotic fragility of RBCs of control and test was observed following administration of 7.1 mg, 10.5 mg and 14 mg/day mefenamic acid to each lizard. Increased osmotic fragility was observed with increase in the amount of dose on day 6 and day 12.

Page(s): 14-18

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 18, Issue: 2, Year: 2005

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