Unusual Sites of Leiomyosarcoma: A Study of 3 Interesting Cases | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2022]

Author(s):

1. Bushra Siddiqui: Department of Pathology, JN Medical College,AMU, Aligarh, Uttar Pradesh,India

2. Shahbaz Habib Faridi: Department of Surgery, JN Medical College,AMU, Aligarh, Uttar Pradesh,India

3. Asfa Shams: Department of Pathology, JN Medical College,AMU, Aligarh, Uttar Pradesh,India

4. Jowairiah Hassan: Department of Pathology, JN Medical College,AMU, Aligarh, Uttar Pradesh,India

Abstract:

Leiomyosarcoma malignant tumours arise from the smooth muscle cells.They are rapidly growing tumours with aggressive behaviour and poor prognosis. Although relatively rare, they pose a diagnostic challenge as they comprise a large spectrum of diagnostic entities. Herein, we describe three cases of leiomyosarcoma developing at unusual sites and posing diagnostic challenges. Our rst case is a leiomyosarcoma developing at the post-burn scar site; the second case is of primary pulmonary leiomyosarcoma, and the third is retroperitoneal leiomyosarcoma. Histopathological examination is not su cient all the time for making the diagnosis of leiomyosarcoma because there is a morphologic overlap with other malignancies. Immunohistochemistry acts as an adjunct to arrive at a de nite diagnosis and hence, proves to be the most important ancillary technique in the diagnosis of such tumours. Though these tumours arise most commonly from the uterine smooth muscle, but rarely encountered at unusual sites posing diagnostic difficulties.

Page(s): 1205-1208

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 32, Issue: 9, Year: 2022

Keywords:

pulmonary , Retroperitoneal , Postburn scar , Leiomyosarcoma

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