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To Find the Correlation of Immunoglobulin G with Severity of Psoriasis
Author(s):
1. Rukhshan Khurshid: Sharif Medical and Dental College LHR, Pakistan
2. Saima Rasheed: Niazi Medical and Dental College, Sargodha. Pakistan
3. Shakil Ahmed: Aziz Fatima Medical and Dental College FSD, Pakistan
4. Huma Ashraf: CMH Lahore medical college & institute of dentistry, LHR, Pakistan
5. Gul-e-Raana: Sharif Medical and Dental College LHR, Pakistan
6. Maira Mahmood: University of Lahore, LHR, Pakistan
Abstract:
Objectives: To find the correlation of immunoglobulin G with severity of psoriasis. Methodology: This cross-sectional descriptive study was conducted at Sir Ganga Ram Hospital Lahore/Niazi Teaching Hospital Sargodha. Study duration was six months from January 2020 to June 2020. One hundred patients of psoriasis (confirmed by Dermatologist) were included in the study. Questionnaire based on age, gender, duration of illness, type and severity of problem etc and biochemical test including immunoglobulin G were filled by consented patients. The study comprised into patients and controls groups. Fifty age matched Subjects with no history of skin disease were taken as controls. For immunological assessment, IgG was measured by the technique of ELISA Results: Mean age of developing of disease was in the range of 36 to 43 years. A few patients have family history with a problem of asthma. High severity of index (59 to 61) in both genders with duration of disease was 4 to 6 years. A direct correlation between level of IgG and disease severity was observed. Conclusion: Increased level of immunoglobulin G and its direct correlation with severity of psoriasis may suggest an activation of 2nd immune defense that try to reduce the severity of disease.
Page(s): 30-33
DOI: DOI not available
Published: Journal: Journal of Aziz Fatimah Medical and Dental College, Volume: 5, Issue: 1, Year: 2023
Keywords:
Psoriasis , Psoriasis , Immunoglobulins , chronic phase , acute phase
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