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Therapeutic Plasma Exchange Combined with Total Thyroidectomy to Rescue a Case of Thyroid Storm Intolerant to Antithyroid Drugs
Author(s):
1. Xiaoxia Hu: Department of Endocrinology, Second Hospital of Lanzhou University,China
2. Haidong Wang: Department of Anesthesiology, Gansu Cancer Hospital,China
3. Jie Li: Department of Endocrinology, Second Hospital of Lanzhou University,China
4. Hong Shi: Department of Endocrinology, Second Hospital of Lanzhou University,China
5. Xia Liu: Department of Endocrinology, Second Hospital of Lanzhou University,China
6. Jirui He: Department of Endocrinology, Second Hospital of Lanzhou University,China
Abstract:
Thyroid storm is a syndrome related to acute exacerbation of thyrotoxicosis for which timely diagnosis and treatment are crucial. Importance of antithyroid drug therapy in thyroid storm patients has been emphasised in clinical treatments for a long time. These patients should receive de nitive therapy for their underlying hyperthyroidism to avoid recurrencaefter controlling thyroid storm. However, the curative e ect of antithyroid medication is sometimes limited because of rare or serious side e ects or failure to control disease progression, resulting in few treatment alternatives. We present a case of an old woman with thyroid storm and antithyroid drug intolerance, which was successfully managed using a combination of plasma exchange and thyroidectomy. It con rms the signi cant bene ts of therapeutic plasma exchange (TPE) when clinical conditions do not allow routine treatment of thyroid storm. This procedure is safe and e ective when performed preoperatively as a rescue measure for thyroid storm patients.
Page(s): 532-534
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 30, Issue: 5, Year: 2020
Keywords:
Total thyroidectomy , Thyroid storm , Drug intolerance , Plasma exchange
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