An experience of steroid in recurrent ethmoidal nasal polyps at tertiary care hospital. | [Journal of Liaquat University of Medical and Health Sciences • 2014]

Author(s):

1. Arsalan Ahmed Shaikh: Department of ENT, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Sindh-Pakistan

2. Muhammad Rafique: Department of ENT, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Sindh-Pakistan

3. Muhammad Shujha Farrukh: Department of ENT, Dow University of Medical Sciences, Karachi, Sindh, Pakistan

Abstract:

OBJECTIVE: To evaluate the effect of preoperative short course of oral steroids followed by postoperative topical nasal steroids sprays on nasal polyp recurrence after classical intranasal Polypectomy. METHODS: Fifty five patients of both genders with symptoms and signs of nasal polyps were included in this prospective study between January 2010 and December 2012. Their ages ranged between 20 and 65 years. The patients were divided into two groups. Group I constituted 30 patients treated by classical sinus surgery (simple nasal polypectomy and intra nasal ethmoidectomy) without oral and local steroid therapy. Group II consisted of 25 patients also treated by intranasal polypectomy but received preoperatively 60mg prednisolone tablets daily for one week and postoperatively topical nasal steroid spray (Mometasone furoate suspension) for three months. All patients were followed up for at least one year. Recurrence of nasal polyps was assessed endoscopically at three, six and twelve months after surgery. Any evidence of nasal polyp formation of whatever size was considered as recurrence. RESULTS: Fifty five patients (35 male and 20 female) with sinonasal polyposis were included in this study. Male to female ratio was 1.75:1. The patients’ age ranged from 20 to 65 years and median age was 45 years; median age was 43 years. Recurrence rates at three; six and twelve months after surgery for the first group of patients were 8.33% (2 patients), 25% (6 patients) and 41.6% (10 patients) accordingly, while the recurrence rates for the second group were 4.1% (1 patient), 8.3% (2 patients) and 12.5% (3 patients) accordingly. CONCLUSIONS: Preoperative short course of oral steroid followed by postoperative nasal steroid spray show significant reduction in the recurrence rate of nasal polyps after intranasal polypectomy.

Page(s): 9-12

DOI: DOI not available

Published: Journal: Journal of Liaquat University of Medical and Health Sciences, Volume: 13, Issue: 1, Year: 2014

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