VALPROATE INDUCED HYPERAMMONEMIC ENCEPHALOPATHY | [Journal of Ayub Medical College • 2022]

Author(s):

1. Wajeeha Qayyum: Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan

2. Zaland Ahmed Yousafzai: Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan

3. Muhammad Shahid Iqbal: Department of Neurology, Rehman Medical Institute,Peshawar ,Pakistan

4. Sohail Khan: Department of Neurology, Rehman Medical Institute,Peshawar- Pakistan

5. Qazi Kamran Amin: Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan

6. Ihtesham Shafiq: Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan

Abstract:

Valproate is a commonly prescribed anticonvulsant drug. It has a potential to cause hyperammonemia even in the presence of normal liver function tests. This hyperammonemic state can lead to encephalopathy referred as Valproate induced hyperammonemic encephalopathy (VHE). Here we present a case of valproate induced hyperammonemic encephalopathy in a young male caused by initiation of valproate therapy.

Page(s): 1038-1039

DOI: 10.55519/JAMC-04-S4-10190

Published: Journal: Journal of Ayub Medical College, Volume: 34, Issue: 4, Year: 2022

Keywords:

encephalopathy , Valproate , neurology

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