The interobserver reproducibility of thyroid cytopathology using Bethesda Reporting System: Analysis of 200 cases. | [Journal of Pakistan Medical Association • 2013]

Author(s):

1. Safina Ahmed: Department of Pathology, Foundation University Medical College, Islamabad, Pakistan

2. Mumtaz Ahmad: Department of Pathology, Foundation University Medical College, Islamabad, Pakistan

3. Masood Ahmad Khan: Department of Pathology, Foundation University Medical College, Islamabad, Pakistan

4. Faiza Kazi: Department of Pathology, Foundation University Medical College, Islamabad, Pakistan

5. Fozia Noreen: FCPS II trainee, Foundation University Medical, College, Islamabad, Pakistan

6. Samia Nawaz: FCPS II trainee, Foundation University Medical, College, Islamabad, Pakistan

7. Iram Sohail: FCPS II trainee, Foundation University Medical, College, Islamabad, Pakistan

Abstract:

Objective: To determine interobserver reproducibility of thyroid cytopathology in cases of thyroid fine needle aspirates.Methods: The retrospective, descriptive study, was conducted at the Foundation University Medical College, Islamabad, using cases related to period between 2009 and 2011. A total of 200 cases of fine-needle aspirations were retrieved from the archives. Three histopathologists independently categorised them into 6 groups according to Bethesda reporting system guidelines without looking at previous reports. Kappa statistics were used for analysis of the results on SPSS 17. Results: Of the 200 patients, 194 (97%) were females and 6 (3%) were males. The overall mean age of patients was 46±20 years. Kappa value calculated for observer-1 and observer-2 was 0.735; for observer-1 and observer-3, 0.841; and for observer-2 and observer-3, 0.838, showing substantial interobserver agreement. Histopathological correlation was available, for 39(19.5%). Of these cases, 5(13%) were `non-diagnostic, 20(51%) `benign, 2(5%) `atypia of undetermined significance/follicular lesion of undetermined significance, 6(15%) `follicular neoplasm, 1(3%) `suspicious for malignancy, and 5(13%) `malignant. Conclusions: Good overall interoberver agreement was found, but discordance was seen when certain categories were analysed separately.

Page(s): 1252-1255

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 63, Issue: 10, Year: 2013

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