Allgrove Syndrome: Case Report of 7 Years Old Boy from Bahawalpur. | [Journal of Pakistan Medical Association • 2018]

Author(s):

1. Sumera Akram: PGR Paediatrics Department, Bahawal Victoria Hospital, Pakistan

2. Muhammad Ahmed Khan: ENT, CMH Bahawalpur Cant, Bahawalpur, Pakistan

3. Abdul Rehman: Paediatrics, Bahawal Victoria Hospital, Pakistan

Abstract:

Allgrove syndrome is a rare autosomal recessive syndrome of unknown prevalence. The first case of Allgrove syndrome was reported in 1978 by Allgrove. It is characterized by triad of achalasia, alacrima and adrenal hypoplasia. There are also associated autonomic and neurological manifestations. We report the case of a 7 years old boy being treated for achalasia cardia, presented with fits and altered sensorium which on further investigations was found to be due to adrenal insensitivity (Raised ACTH level, low Cortisol level, and normal Aldosterone and Renin ratio). He also had undiagnosed alacrima since birth, mild degree of hearing loss and autonomic instability in the form of episodic hypertension.

Page(s): 1260-1262

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 68, Issue: 8, Year: 2018

Keywords:

Keywords are not available for this article.

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