The reaction of harmaline with cyclohezanone-oxalyl chloride adduct - A one step synthesis of reserpine analogues. | [Journal of Chemical Society of Pakistan • 1984]

Author(s):

1. Atta-Ur-Rehman: HEJ Postgraduate Institute of Chemistry, University of Karachi, Karachi, Pakistan

2. S. Firdous: HEJ Postgraduate Institute of Chemistry, University of Karachi, Karachi, Pakistan

Abstract:

The reaction of cyclohexanon with oxalylchloride affords the adduct (3). Reaction of (3) with harmaline (1) affords a high yield one step synthesis of the pharmacologically interesting skeletal system (5) which bears the carbon frame-work of reserpine

Page(s): 17-26

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 6, Issue: 1, Year: 1984

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