Variation in antioxidant activity and phenolic and flavonoid contents in the flowers and leaves of ghaneri (Lantana camara L.) as affected by different extraction solvents. | [International Journal of Pharmacology • 2013]

Author(s):

1. Farooq Anwar: Department of Chemistry, University of Sargodha, Sargodha, Pakistan

2. Nusrat Shaheen: Department of Chemistry & Biochemistry, University of Agriculture, Faisalabad, Pakistan

3. Ghulam-Shabir: Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad, Pakistan;Environmental Biotechnology Divisions, National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan

4. Muhammad Ashraf: University College of Agriculture, University of Sargodha, Sargodha, Pakistan

5. Khalid M. Alkharfy: Department of Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

6. Anwarul-Hassan Gilani: Department of Biological and Biomedical Sciences, Aga Khan University, Karachi;Department of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia

Abstract:

The current study reports variation in antioxidant activity and phenolic and flavonoid contents in the flowers and leaves of a medicinal al herb Ghaneri (Lantana camara L.) as affected by different extraction solvents (80% methanol, 80% ethanol, absolute methanol and absolute ethanol). The antioxidant activity was assessed by measuring the reducing power, inhibition in linoleic acid peroxidation and 2, 2-dipheny1-1-picrylhydrazyl radical (DPPH.) scavenging activity. Of the extracts tested, flower extract produced by 80% methanol possessed maximum amount of total phenolics (21.4 g GAE/100 g DW), total flavonoids (13.8 g CE/100 g DW), reducing power (0.095 for extract concentration of 1.0 mg mL-1), inhibition of linoleic oleic acid peroxidation (83.3%) and DPPH radical scavenging activity (72.3%). A significant difference was observed for phenolic and flavonoid contents and antioxidant activity in relation to different extraction solvents and plant parts analyzed (pL. camara as a rich source of natural antioxidants for development of functional foods and nutraceutical applications.

Page(s): 442-453

DOI: DOI not available

Published: Journal: International Journal of Pharmacology, Volume: 9, Issue: 7, Year: 2013

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