To evaluate comparative values of HDL cholesterol among male and female patients of type 2 diabetes. | [Isra Medical Journal • 2014]

Author(s):

1. Muhammad Ahmad Alamgir: Bahawal Victoria Hospital, Bahawalpur, Pakistan

2. Aftab Jamil: Quaid-e-Azam Medical College, Bahawalpur, Pakistan

3. Saleem Akhtar: Quaid-e-Azam Medical College, Bahawalpur, Pakistan

4. Irum Mustafa: Quaid-e-Azam Medical College, Bahawalpur, Pakistan

Abstract:

OBJECTIVES: To assess and compare the HDL Cholesterol among male and female type 2 diabetics and to look for the blood pressure and glycemic stats between both genders. STUDY DESIGN: An observational comparative prospective study. PLACE AND DURATION: The study was conducted in Medical Unit-2 of Bahawalpur Victoria Hospital over a period of 6 months from June 2012 to December 2012. METHODOLOGY: A sample size of hundred diagnosed cases of type 2 diabetes was collected. Those who had hyperlipidaemia due to secondary causes like nephrotic syndrome, hypothyroidism and drugs were excluded. Fasting blood samples were collected for sugar and lipid profile. All collected data was analyzed through software SPSS version 10. RESULTS: Female patients were found to be overweight and hypertensive and they had uncontrolled hyperglycemia as well. The mean values of lipoprotein were deranged in females as compared to males. By applying NCEP ATP III criterion, lipid level were classified into different risk categories. In female patient the mean concentrations of HDL-C was 32+2.4mg/dL (T-Value = -23.57 very highly significant) and was in high risk category while LDL-C was 191+31.81mg/dL (T-Value = -2.01 significant) and was in borderline risk. LDL: HDL ratio was 6.0 and significantly raised. Triglycerides were within normal range. In male patients the mean concentration of LDL was borderline risk 174+41mg/dL(T-Value = 13.2) while HDL-C was 40mg/dL (T-Value = -6.53), both in borderline category. LDL: HDL ratio was also in acceptable range in males. Triglycerides values turned out to be within normal range in both gender. CONCLUSION: HDL cholesterol was frequently reduced and was in high risk category in female diabetic patients as compared to male counterparts and LDL values were borderline. Hence they are at more risk of complications as they were hypertensive and had more uncontrolled hyperglycemia as well.

Page(s): 3-5

DOI: DOI not available

Published: Journal: Isra Medical Journal, Volume: 6, Issue: 1, Year: 2014

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