Author(s):
1. Ayesha Waheed:
Pakistan Institute of Medical Sciences, Islamabad, Pakistan
2. Iqtada Haider Shirazi:
Pakistan Institute of Medical Sciences, Islamabad, Pakistan
3. Asma Mustafa:
Pakistan Institute of Medical Sciences, Islamabad, Pakistan
4. Yasir Waheed:
Pakistan Institute of Medical Sciences, Islamabad, Pakistan
Abstract:
Objective: Neonatal hyperbilirubinemia is a common condition affecting 60% of the term and 80% of the preterm neonates. Bilirubin can be neurotoxic, when its concentration rises more than 20mg/dl which occurs in 2% of infants. The most prevalent therapeutic method for managing infantile icterus and preventing its complications is phototherapy and exchange transfusions at higher bilirubin levels. Material and Methods: A quasi experimental study was conducted on 60 neonates with hyperbilirubinemia. They were randomly divided into two groups. Group A (n=30) received zinc sulphate 5mg twice daily for 5 days, in addition to phototherapy. Group B (n=30) received phototherapy. Total serum bilirubin was calculated at 0, 24 and 72 hours for both groups. Results: No significant difference was found in total serum bilirubin at 0, 24 and 72 hours in both groups (p=0.46, 0.39 and 0.20 respectively) Conclusion: Oral zinc sulphate is not effective in the treatment of hyperbilirubinemia in neonates.
Page(s):
36-39
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Pathology, Volume: 30, Issue: 2, Year: 2019
Keywords:
Neonate
,
jaundice
,
zinc sulphate
,
Hyperbilirubinemia
,
Phototherapy
,
Physiological Jaundice
References:
References are not available for this document.
Citations
Citations are not available for this document.