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Immune Boosting Potential of Selected Medicinal Plant Species against Pandemics like Covid 19
Author(s):
1. Irum Khalid: Department of Botany, PMAS-Arid Agriculture University Rawalpindi, Rawalpindi 46300, Pakistan
2. Yamin Bibi: Department of Botany, PMAS-Arid Agriculture University Rawalpindi, Rawalpindi 46300, Pakistan
3. Neelum Naheed: Department of Botany, PMAS-Arid Agriculture University Rawalpindi, Rawalpindi 46300, Pakistan
4. Ayesha Khanum: Department of Botany, PMAS-Arid Agriculture University Rawalpindi, Rawalpindi 46300, Pakistan
5. Abdul Qayyum: Department of Agronomy, The University of Haripur, Haripur 22620, Pakistan
Abstract:
Infectious diseases and malnutrition have always been a great challenge especially in developing countries as they adversely affect the human immune system. Medicinal plants play a vital role for enhancement of immunity. Thymus vulgaris, Aloe vera, and Asparagus officinalis have been used for the treatment of various skin diseases, respiratory problems, UTI, cough, wounds, ulcers, inflammation as well as diabetes. The current study aims to scientifically validate the immune boosting potential of these medicinal plants. Crude extract of plant material was prepared by using cold maceration technique. Phytochemical screening of methanolic plant extracts revealed the presence of alkaloids, flavonoids, tannins, saponins, and phenolics. Steroids was present in methanolic extracts of A. officinalis and T. vulgaris while absent in Aloe vera which indicated the medicinal value of studied plants. Mineral analysis of these medicinal plants reveals the presence of good quantity of Na, K, Zn, Mn, Ca, Fe, Cd, and Cr thus enhances the nutritional value of plants. Highest amount of K was presnt in A. officinalis (60.95ppm) while high Mn content was present in Aloe vera (81.08ppm). Quantity of Zinc (52.33ppm) and Cd (20.36ppm) was high in T. vulgaris. Antioxidant assay of A. officinalis showed good scavenging potential (57.53%) followed by T. vulgaris (54.14%) and Aloe vera (52.54%). ABTS, ferric reducing power assay and revealed the prominent activity shown by Aloe vera (63.30%, 51.03%) as compared to T. vulgaris (56.25%, 46.52%,) and A. officinalis (49.03%, 48.44%). Cytotoxicity results revealed the highest mortality rate of A. officinalis as compared to other two plant extracts. Adaptive immune response test revealed enhancement of cytokines and antibodies production in Aloe vera as compared to other two extracts
Page(s): 73-73
DOI: DOI not available
Published: Journal: Abstract Book on Second International Conference on Recent Approaches in Plant Sciences (RAPS-23) 4-5 May 2023 , Volume: 0, Issue: 0, Year: 2023
Keywords:
Phytochemicals , antioxidant , minerals , Thymus vulgaris , Aloe vera , in silico , Asparagus officinalis
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