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4-(3-methylbenzofuran-2-y1)-2-hydioxytetro-nimide and its derivatives: Aryl analogues of imino-L-aascorbic acid.
Author(s):
1. Hassan M. Mokhtar: Institute of Chemistry Nicolus Copernicus University, Torum, Poland
2. J. Wojtanis: Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
Abstract:
The synthesis of 4-(3-methylbenzofuran-2-y1)-2-hydroxytetrorimide (I), its monoacyl derivatives (Ill), and hydrazone (VI) is described. The oxidation of the tetronimide (I) with nitrous acid yielded 2,3 dioxo-4-(3-methylbenzofuran-2-yl)butyro-1, 4-lactone (VII). Reaction of the lactone (VII) with acylhydra-zines afforded bis acylhydrazones (VIII). In the case of arylhydrazines, it gave the corresponding bis-aryl-hydrazones (IX) which were cyclized to 1-ary1-4-aryl-hydrazono-3-(hydroxy (3-methylben-zofuran-2-yl)methyl) pyrazoles-5-ones (X). Furthermore, the reaction of compound (VII) with o-phenylenediamine gave a quinoxaline derivative (XI).
Page(s): 80-84
DOI: DOI not available
Published: Journal: Pakistan Journal of Scientific and Industrial Research, Volume: 29, Issue: 2, Year: 1986
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