Abstract:
Objective: To see the effect of oral paracetamol and clonidine on pediatric preoperative anxiety in adenotonsillectomy. Methodology: The participants of this double blind clinical trial study consisted of 120 children. Their age range was between 3-12 years. They were in ASA class I of anesthesia and were chosen for elective adenotonsillectomy in Qods hospital in Qazvin, Iran. The patients were randomly divided in three equal groups. One group received paracetamol 20 mg/kg, another group received 4mg/kg clonidine orally 60-90 minutes before operation and the third group received placebo. As the first step, in order to do the statistical analysis, intensity of preoperative anxiety had been evaluated by Modified-Yale Preoperative Anxiety Scale (m-Yale PAS) and data were transformed to the SPSS software. Then different statistical procedures like Chi-square, One way Annova and Tukey test were performed. Results: There was no significant difference (statistical) of age, weight and sex among three groups. Mean score of anxiety was significantly lower in paracetamol and clonidines groups than placebos group, but there was no significant statistical difference between paracetamol and clonidines groups in decreasing preoperative anxiety score. Conclusions: Oral paracetamol like oral clonidine decreases preoperative anxiety score. Thus one can use paracetamol instead of clonidine.
Page(s):
458-461
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Medical Sciences, Volume: 25, Issue: 3, Year: 2009