The 2011 dengue haemorrhagic fever outbreak in Lahore - an account of clinical parameters and pattern of haemorrhagic complications. | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2013]

Author(s):

1. Shahid Ahmed: Department of Medicine, Combined Military Hospital, Lahore Cantt, Pakistan

2. Wasim Wali Mohammad: Department of Medicine, Combined Military Hospital, Lahore Cantt, Pakistan

3. Faran Hamid: Department of Medicine, Combined Military Hospital, Lahore Cantt, Pakistan

4. Amim Akhter: Department of Medicine, Combined Military Hospital, Lahore Cantt, Pakistan

5. Raja Kamran Afzal: Department of Medicine, Combined Military Hospital, Lahore Cantt, Pakistan

6. Asif Mahmood: Department of Medicine, Combined Military Hospital, Lahore Cantt, Pakistan

Abstract:

OBJECTIVE: To describe the frequency and outcome of dengue haemorrhagic fever (DHF) cases and determine the association of clinical and laboratory parameters with haemorrhagic complications. STUDY DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: Combined Military Hospital, Lahore, from August to November 2011. METHODOLOGY: Clinical profile and outcome of 640 adult patients hospitalized with a strong clinical suspicion of dengue fever (DF) was evaluated. Based on serological confirmation, these patients were divided into confirmed DF and probable DF cases. They were also categorized according to severity into dengue fever (DF), dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) cases according to WHO guidelines. After detailed clinical evaluation, blood samples were taken for a complete blood count, urea, creatinine, sodium, potassium, bilirubin, alanine aminotransferase (ALT), prothrombin time (PT) and activated partial thromboplastin time (APTT). Patients were managed according to standard protocols with intravenous fluids and symptomatic treatment. SPSS 18 was used for statistical analysis of clinical data. Comparison of features among the groups was made using chi-square or t-test with significance at p

Page(s): 463-467

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 23, Issue: 7, Year: 2013

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