Synthesis, crystal structure and biological activity of n-(5-(o-tolyl)-1, 3, 4-thiadiazol-2-yl)cyclopropanecarboxamide. | [Journal of Chemical Society of Pakistan • 2013]

Author(s):

1. Jian-Ying Tong: College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou, Zhejiang, China

2. Na-Bo Sun: College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou, Zhejiang, China

3. Hong-Ke Wu: College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China

4. Xing-Hai Liu: College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China

Abstract:

A new 1, 3, 4-thiadiazole compound, N-(5-(o-tolyl)-1,3,4-thiadiazol-2-yl) cyclopropanecarboxamide, was synthesized and its structure was confirmed by 1H NMR, MS and HRMS. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound has moderate herbicidal activity against Brassica campestris and fungicidal activities against Sclerotinia sclerotiorum(Lib.) de Bary, Rhizoctonia solanii, Fusarium oxysporum, Corynespora cassiicola, and Botrytis cinerea.

Page(s): 1351-1355

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 35, Issue: 5, Year: 2013

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