Abstract:
The emergence of nanotechnology revolutionized the modern world as it is anintegrated field of science which has transformed the industries, presentedefficient energy solutions and helped us getting different devices and treatmentin the field of medicine. The production and utilization of nanoparticles (NPs)demonstrates significant advancement in nanotechnology owing to the distinctphysicochemical characteristics of NPs including high surface area-to-volumeratio and enhanced reactivity. The antimicrobial together with antioxidant, antilarvicidal,antileishmanial and anticancer properties and catalytic attributes ofiron oxide nanoparticles (IONPs) make them attractive for various applications.The traditional nanoparticle synthetic practices employ toxic substances andexcessive energy has drawn criticism because they have sustainability challengesand has adverse environmental and health impacts. This research studydemonstrates the fabrication of Saxifraga flagellaris sourced IONP aqueousextract because this plant has medicinal importance and pharmacologicalproperties. Different analytical tools such as UV- Visible spectroscopy, SEM,XRD, FTIR confirmed the formation, crystalline structure, size, morphology andadsorbed functional groups on the synthesized nanoparticles. The average sizeof 22.66 nm was recorded utilizing sharp peaks of XRD spectra. The scanningelectron micrograph revealed round shape and agglomerated nature of S.flagellaris mediated IONP. The narrow and distinct peaks of FT-IR exhibits thepresence of Fe?O, C-C, C-O, C-N, C-H, C=C, C-OH and O-H functionalmoieties up on particle surface. Furthermore, different bioactivities revealedsignificant potential of our greenly synthesized NPs. The disc diffusiontechnique confirmed promising bactericidal and fungicidal activities against allselected microbial strains. The asynthesized nanoparticles displayed moderatepotential against HepG2 liver cancer cells and significant potency against brineshrimps (IC50: 33 %). Additionally, the S-Flagellaris sourced IONPssuccessfully degraded 63% selected azo dye; methylene red dye. Overall, thefabricated S flagellaris-IONPs have shown potential bioactivities and need to befurther evaluated for in depth in-vitro and in-vivo investigations to createpharmaceutical or dug formulation.
Page(s):
56-56
DOI:
DOI not available
Published:
Journal: 4th International Conference of Sciences “Revamped Scientific Outlook of 21st Century, 2025” , November 12,2025, Volume: 1, Issue: 1, Year: 2025
Keywords:
antifungal activities
,
Antimicrobial activities
,
anticancer activity
,
Saxifraga flagellarisIONPs