Acid catalyzed solvent free synthesis of new 1-Acyl-4-benzhydryl substituted pyrazoles. | [Journal of Chemical Society of Pakistan • 2016]

Author(s):

1. Muhammad Sher: Department of Chemistry, Allama Iqbal Open university, Islamabad, Pakistan

2. Ejaz Ahmed: Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan

3. Tasneem Kausar: Department of Chemistry, Allama Iqbal Open university, Islamabad, Pakistan

4. Nadia Riaz: Department of Chemistry, Allama Iqbal Open university, Islamabad, Pakistan

5. Muhammad Arshad: Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan

6. Ahsan Sharif: Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan

7. Azeem Intisar: Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan

8. Javeed Akhtar: Department of Physics, Polymers and Materials Synthesis PMS Laboratory, COMSATS, Institute of Information Technology, Islamabad, Pakistan

9. Muhammad Aamir: Department of Chemistry, Allama Iqbal Open university, Islamabad, Pakistan

Abstract:

A convenient, cost effective and environmentally benign methodology has been developed, which delivered fourteen new 1-acyl-4-benzhyrdyl substituted pyrazole derivatives under solvent free conditions. Target compounds were synthesized in good to excellent yields simply by grinding reactants in a pestle and mortar with catalytic amount of conc. H2SO4. All the newly formed compounds were fully characterized with the help of detailed spectroscopic techniques including FTIR, NMR and GC-MS.

Page(s): 1203-1210

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 38, Issue: 6, Year: 2016

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