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Antibacterial and Antibiofilm Activities from Extracts of Selected Cholistani Plants
Author(s):
1. Summayya Anwar: Institute of Molecular Biology and Biotechnology, The University of Lahore, Pakistan, Lahore, Pakistan
2. Mirza Imran Shahzad: Institute of Biochemistry, Biotechnology, and Bioinformatics,The Islamia University of Bahawalpur, Pakistan
Abstract:
The Cholistani plants are used as a vital source of medicines by local nomads since long time. Recently, many pharmacological studies like antibacterial, antiviral, antifungal, and antidiabetic aredone, but very few chemistry-based approaches are available. The current study was designed to evaluate the antibacterial potentials of extracts of Cholistani plants. Aqueous, ethanol, and n-hexane extracts were prepared. Extracts are made on the basis of solvent polarity. All the extracts were tested for antibacterial activities through disc diffusion method. The Minimum Inhibitory Concentration (MIC) of each positive extract was measured. The results indicated that the aqueous extract of these plants was more effective than others. The overall trend of antibacterial activity was as follows aqueous >n-hexane >ethanol extracts in terms of solvent. In terms of bacteria, almost all extracts were effective against Klebsiella pneumonia. The overall antibacterial trend was Klebsiella pneumonia > Proteus vulgaris > Staphylococcus aureus > Escherichia coli > Pseudomonas aeuriginosa. The results indicate that Cholistani plants are a rich source of antibacterial agent(s) and can be used in crude or purified form.
Page(s): 54-54
DOI: DOI not available
Published: Journal: Abstract Book on Global Science Technology and Management Conference, Volume: 0, Issue: 0, Year: 2023
Keywords:
E coli , Antibacterial activity , Cholistani plants , Kpneumonia
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