A five-year epidemiologic study of autoimmune bullous diseases in Southeast of Iran | [Journal of Pakistan Association of Dermatologists • 2023]

Author(s):

1. Behzad Iranmanesh: Department of Dermatology, Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

2. Nazanin Zeinali Nezhad: Kerman University of Medical Sciences, Kerman, Iran.

3. Fatemeh Shamsi Ghoshki: Kerman University of Medical Sciences, Kerman, Iran.

4. Amirhossein Shahpar: Kerman University of Medical Sciences, Kerman, Iran.

5. Rezvan Amiri: Department of Dermatology, Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran

6. Seyed Ali Hosseini: School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

7. Najmeh Ahramiyanpour: Department of Dermatology, Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.; Kerman University of Medical Sciences, Kerman, Iran

Abstract:

Background Autoimmune bullous diseases (AIBDs) are a group of chronic blistering diseases that affect mucocutaneous membranes. These diseases are common worldwide and affect males and females of all races. Treatment options include corticosteroids, rituximab, and topical agents. We evaluated the epidemiology of AIBD in Kerman, Iran, over a five-year period. Methods This retrospective study was conducted on 100 patients diagnosed with an AIBD between 2015-2020. All patients were included in this study by census method. Factors like age, sex, disease type, and age at diagnosis were evaluated. Data analyses were performed using SPSS version 26. Results One hundred patients participated in this study, and the male-to-female ratio was 1:1.08. The mean age of participants was 51.99±19.52 years, and the mean age at diagnosis was 49.19±8.31. Out of 100 patients, 82 suffered from pemphigus disease (70 pemphigus vulgaris; 12 pemphigus foliaceus), 17 had bullous pemphigoid, and one patient had pemphigus gestationis. Conclusion In many countries, pemphigus is the most common AIBD. Although AIBDs are uncommon, the diagnosed cases increase with age.

Page(s): 1031-1043

DOI: DOI not available

Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 33, Issue: 3, Year: 2023

Keywords:

Abstract , Bullous diseases , eolgtAutoimmune

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