Author(s):
1. Manimekalai Periyasamy:
Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
2. Pon Divya Bharathi:
Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
3. Mullangi Chenchu Vinatha:
Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune condition, affecting multiple organs and tissues by autoantibodies and immune complexes. Hematologic manifestations of SLE include anemia, thrombocytopenia and leukopenia. The most common type of anemia seen in SLE is anemia of chronic disease. Thrombotic microangiopathic hemolytic anemia (TMHA) in SLE is very rare. Incidence of TMHA in children with SLE is common compared to adult cases of SLE. Manifestations of TMHA include presence of schistocytes in the peripheral smear, elevated bilirubin levels, elevated LDH and negative coombs test. This case report focuses on 25-year-old female diagnosed concomitantly with SLE and TMHA, and treated with steroids, blood transfusions, megakaryocyte growth factors and antibiotics.
Page(s):
163-164
Published:
Journal: Gomal Journal of Medical Sciences, Volume: 19, Issue: 4, Year: 2021
Keywords:
Thrombocytopenia
,
Anemia
,
Leukopenia
,
Red Blood Cells
,
Systemic lupus erythematosus
,
Hemolytic anemia
,
Coombs test
,
HemolyticUremic Syndrome
,
Microangiopathic Hemolytic Anemia
,
Autoantibodies
References:
References are not available for this document.
Citations
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