Adenosine deaminase organic effectors in normal and abnormal cerebrospinal fluid. | [Rawal Medical Journal • 2007]

Author(s):

1. Amina Hamed Ahmad Alobaidi: Departments of Biochemistry and Medicine, College of Medicine, Tikrit University, Tikrit, Iraq

2. Abdul Ghani Mohamed Ali Alsamarai: Departments of Biochemistry and Medicine, College of Medicine, Tikrit University, Tikrit, Iraq

3. Abdul Monem Hamad Majed Alsamarai: Departments of Biochemistry and Medicine, College of Medicine, Tikrit University, Tikrit, Iraq

Abstract:

To study the effect of the organic substances on adenosine deaminase (ADA) activity in normal and abnormal cerebrospinal fluid (CSF). Methods: Various concentrations of 2-mercaptopurine, Ame”tycine, Adenosine analogues (Guanine, Thymine ) and ATP were tested to see their effect on ADA activity in normal and abnormal CSF. Results: ADA activity in normal and abnormal CSF was remarkably decreased with the increasing of concentrations of substances tested. Conclusion: These effects may have important therapeutic implications.

Page(s): 146-149

DOI: DOI not available

Published: Journal: Rawal Medical Journal, Volume: 32, Issue: 2, Year: 2007

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