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Utility of difusion weighted Magnetic Resonance Imagining to detect non-palpable undescended testis
Author(s):
1. Nasreen Naz: Department of Radiology, DUHS, Ojha Campus, Karachi, Pakistan.
2. Ayesha Walid: Department of Radiology, DUHS, Ojha Campus, Karachi, Pakistan.
3. Anila Rahim: Department of Radiology, DUHS, Ojha Campus, Karachi, Pakistan.
4. Komal Lajpat: Civil Hospital Karachi (CHK), Dow University of Health Sciences (DUHS) Karachi, Pakistan
Abstract:
Objective: To assess the efectiveness of difusion-weighted magnetic resonance imaging (DW-MRI) in the detection of non-palpable undescended testis (NPUT) and to compare DW-MRI results with surgical findings. Methods: This descriptive, cross-sectional study was carried out at Dow Institute of Radiology, Dow University of Health Sciences. Karachi on a cohort of patients who underwent DW-MRI for suspected NPUT between 15th September, 2022 to 16th March, 2023. The study included 175 boys below the age of 16 years with history of clinically non-palpable testes. MRI scans were acquired using additional DWI sequence. Two radiology faculty of more than five years of experience independently evaluated the DW-MRI images for the presence or absence of testes in its normal anatomical position, abnormal location, side and size of testes. Results: Out of the 175 patients, DW-MRI successfully detected 128 (73.1%) non-palpable undescended testes. Statistical analysis in clinically detected cases of showed sensitivity of NPTU 0.8%, specificity of 92.5%, diagnostic accuracy 94.29%, positive predictive value 97.7%, and negative predictive value 84.1% for localizing undescended testes with Difusion Weighted DW-MRI taking surgical findings as gold standard. Conclusion: DWI sequences complement the conventional MRI, increasing its sensitivity and diagnostic accuracy. By facilitating early and accurate diagnosis, DW-MRI has the potential to streamline patient management, reduce unnecessary surgical exploration, and ultimately improve the long-term reproductive health and quality of life for individuals with undescended testes.
Page(s): 2069-2073
Published: Journal: Pakistan Journal of Medical Sciences, Volume: 40, Issue: 9, Year: 2024
Keywords:
Undescended testis , Nonpalpable Undescended Testis NPUT , DifusionWeighted Magnetic Resonance Imaging DWMRI
References:
[1] Sun T,Xu W,Xu H,Chen Y,Niu Y,Wang D .2022 .Hormonal therapy is effective and safe for cryptorchidism caused by idiopathic hypogonadotropic hypogonadism in adult males. Front Endocrinol, 10 : 1095950.
[2] Gill MS,Shah SH,Soomro IN,Kayani N,Hasan SH .2000 .Morphological pattern of testicular tumors. J Pak Med Assoc, 50(4) : 110-112.
[3] Shepard CL,Kraft KH .2017 .The nonpalpable testis: a narrative review. J Urol, 04(6) : 1410-1417.
[4] Abd-ElGawad EA,Abdel-Gawad EA,Magdi M,Al-Minshawy SM .2014 .Magnetic resonance imaging for detection of non-palpable undescended testes: Diagnostic accuracy of diffusion-weighted MRI in comparison with laparoscopic findings. Egypt J Radiol Nucl Med, 10(1) : 205-210.
[5] Al-Kayat RH .2013 .The role of diffusion-weighted MRI in the evaluation of non-palpable undescended testis. Mustansiriya Med, 12(2) : 1.
[6] Kurz D,Tasian G .2016 .Current management of undescended testes. Curr Treat Options Pediatr, 10(1) : 43-51.
[7] Wakeel Al,Azab AM,Soliman SM,MM SM .2019 .The diagnostic value of magnetic resonance imaging in the diagnosis of nonpalpable undescended testis. Menoufia Med, 267(1) : 17.
[8] Moriya K,Nakamura M,Nishimura Y,Nishida M,Kudo Y,Kanno Y .2018 .Impact of preoperative ultrasonographic evaluation for detection of a viable testis in patients with a unilateral nonpalpable testis. J Ultrasound Med, 10(7) : 1665-70.
[9] Tasian GE,Copp HL. .2011 .Diagnostic performance of ultrasound in nonpalpable cryptorchidism: a systematic review and meta-analysis. Pediatrics, 10(1) : 1800-128.
[10] Manganaro L,Saldari M,Pozza C,Vinci V,Gianfrilli D,Greco E .2018 .Dynamic contrast enhanced and diffusion-weighted MR imaging in the characterisation of small, nonpalpable solid testicular tumours. Eur Radiol, 10(2) : 554-564.
[11] Kumar K,HG V,Reddy R. .2018 .Clinical study and role of diagnostic laparoscopy in the management of undercended testis: our experience. J Surg, 14(2) : 61-65.
[12] MD M,MD W,Yassin A .2017 .Role Of Diffusion-Weighted Magnetic Resonance imaging in detection of non-palpable undescended testes. Int J Adv Res, 5(7) : 1367-1374.
[13] Mohammed NE,Badwey ME,Nagla SA,Dawoud RM .2022 .Diffusionweighted imaging and conventional magnetic resonance imaging for detection of non-palpable undescended testis. Egypt J Radiol Nucl Med, 10(1) : 1-9.
[14] Fazal K,Hussain S,Khan F,Ullah I,Tahir MJ,Mehmood Q .2021 .To determine the sensitivity, specificity, and diagnostic accuracy of diffusion-weighted MRI in localization of non-palpable undescended testes taking laparoscopic findings as the gold standard: A cross-sectional study from Pakistan. Ann Med Surg, 10 : 10316.
[15] Chen Z,Chu Y,Hu Y. .2023 .Comparison of clinical outcomes between laparoscopic orchiopexy and open orchiopexy in the treatment of palpable undescended testes. Pak J Med Sci, 10(3) : 7371-789.
[16] Hutson JM,Thorup JM,Beasley SW JM .2016 .Classification and causes of undescended testes in humans. In: Descent of the Testis, : 45-67.
[17] Krishnaswami S,Fonnesbeck C,Penson D,McPheeters ML .2013 .Magnetic resonance imaging for locating nonpalpable undescended testicles: a meta-analysis. Pediatrics, 10 : 0073-e1916.
[18] Ali SA,Mansour MG .2016 .Efficiency of combined diffusion weighted imaging and conventional MRI in detection of clinically nonpalpable undescended testes. Egypt J Radiol Nucl Med, 09(1) : 251-256.
[19] Nasim R,Yasin A,Kaleem M. .2024 .Role of Diffusion Weighted Imaging in Localization of Non-palpable Undescended Testes Taking Laparoscopic Finding as Gold Standard. Esculapio J SIMS, 10(1) : 43-47.
[20] Tseng CS,Chiang IN,Hong CH,Lu YC,Hong JH,Chang HC,Huang KH,Pu YS .2017 .Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle. Sci Rep, 10(1) : 1-6.
[21] Sheikh A,Mirza B,Ahmad S,Ijaz L,Kayastha K,Iqbal S K .2012 .Laparoscopic management of 128 undescended testes: our experience. Afr J Paed Surg, 10(2) : 99393-6725.
[22] Emad-Eldin S,Abo-Elnagaa N,Hanna SA,Abdel-Satar AH .2016 .The diagnostic utility of combined diffusion-weighted imaging and conventional magnetic resonance imaging for detection and localization of non palpable undescended testes. J Med Imaging Radiat Oncol, 10(3) : 12458-9485.
[23] Mohammed NE,Badwey ME,Nagla SA,Dawoud RM .2022 .Diffusionweighted imaging and conventional magnetic resonance imaging for detection of non-palpable undescended testis. Egypt J Radiol Nucl Med, 10(1) : 169.
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