A review on Aluminum phosphide (Rice Tablets) Poisoning; From Exposure to the Applicable and New Strategies of Clinical Management | [Advancements in life sciences • 2021]

Author(s):

1. Aliasghar Manouchehri: Department of Internal Medicine, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol ,Iran

2. Shiva Ghareghani: Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

3. Shabnam Shamaei: Department of Chemistry,Khorramabad Branch,Islamic Azad University,Khorramabad, Iran

4. Maede Nilechi: Department of Biology,Science and ResearchBranch, Islamic AzadUniversity, Tehran , Iran

5. Fatemeh Bossaghzadeh: Department of Biology,Dezful Branch, Islamic Azad University, Dezful , Iran

Abstract:

Rice tablets (especially aluminum phosphide) as a solid fumigant pesticide is one of the major areas of interest within the field of pesticide poisoning due to high fatality. It is commonly used in grain storage ice tablets (especially aluminum phosphide) as a solid fumigant pesticide is one of the major areas of places including silos, warehouses, and grain transporting systems such as ships to control damages of pests and rodents. Unfortunately, it is considerably consumed for suicidal purpose in developing countries because of the ease of access. Aluminum phosphide (ALP) has been conceived as the most mortal one among others and accounts for many deaths each year. ALP toxicity is associated with phosphine gas liberation which is highly toxic and may cause various toxicities in all body organs, especially in cardiovascular and respiratory systems. As there is no certain antidote to prevent human's death, hence having thorough information about this pesticide is required. Thus, in this article physiochemical features of rice tablets, various toxicological, clinical/pathological impacts of ALP on human body and also applicable and new strategies of its managements have been highlighted. Eventually, gathering all published information about ALP intoxication till date demonstrated that restricted preventative measures plus early and improved management protocols can limit the organ injuries and mortality.

Page(s): 326-332

DOI: DOI not available

Published: Journal: Advancements in life sciences, Volume: 8, Issue: 4, Year: 2021

Keywords:

pesticide , phosphine , Management strategies , Aluminum phosphide , Rice tablet , Toxicity of ALP , Human poisoning

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