Author(s):
1. Zahid Bashir:
Departmentof Food Science and Technology, UCP, Lahore, Pakistan
2. Kanza Aziz Awan:
Departmentof Food Science and Technology, UCP, Lahore, Pakistan
Abstract:
An imbalance in the population of microbes that live in the gut has been related to bothsystemic inflammation and metabolic problems. There is evidence to indicate that a dysfunctionin the gut microbiome known as dysbiosis contributes to the genesis of type 2 diabetes viaregulating metabolic pathways. Indications interact with dietary components regulate intestinal permeability and affect the metabolism of glucose and lipids insulin sensitivity and energybalance. Most studies from the Systematic Literature Review (SLR) revealed that faecal shotgunmetagenomics and a randomized clinical trial of isocaloric diets were used to demonstrate that only as ubset of Short Chain Fatty Acids (SCFA) producing bacteria was favored by dietary fibre whereas the majority of other putative producers were diminished and in some cases unchangedin patients. In addition the various fiberpromoted SCFA manufacturers' enhanced glucagon-like peptide-1 secretion and decreased haemoglobin A1C. Multi plephysiological path ways relevant to human health have been found to be influenced by gut microbiota and its metabolites. SCFA aremicrobial meta bolites that modulate many metabolic processes. On the other hand some research revealed that food could influence gut microbiota makeup and activity thus regulating the risk of obesity insulin resistance and type 2 diabetes which are all examples of metabolic illness. The studies concluded that dietary fibre might play a significant role among dietary components dueto its prebiotic effect on fibre-fermenting bacteria which may boost SCFA synthesis. The goal of this review was to synthesize and evaluate current research on the role of dietary fibre in modulating the link between glucose metabolism and microbiota composition in people. The examination of data from observational studies and randomized dietary interventions investigated the connection between Type 2 Diabetes gut microbiota short-chain fatty acids and glucose metabolism. The mechanisms behind this relationship were also addressed.
Page(s):
364-364
DOI:
DOI not available
Published:
Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
Gutmicrobiota dysbiosis Short Chain Fatty Acids SCFA faecal shot gun meta genomics is ocaloric diets
References:
References are not available for this document.
Citations
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