Abstract:
This study reports synthesis of a-mangostin mediated silver nanoparticles (AgNPs)using various ratios of a-mangostinand silver salt solution under the condition of stirring and heating, sunlight, heating, and incubation. Also, antioxidant, anticancer, and catalytic (in dyes degradation)potential of synthesized AgNPs was investigated. AgNPs synthesisand sizewas confirmed by surface plasmon resonance (SPR) band in UV-Visible spectroscopic analysis, scanning electron microscopy (SEM), and atomic force microscopy (AFM) techniques. From the results, it was found that 1:10 volume ratio of a-mangostin and salt solution under stirring and heating yielded prominent AgNPs, which exhibited sharp SPR band at 420-425 nm having a size of62 nm as determined by UV-Visible, SEM and AFM instrumental techniques. The synthesized AgNPs and a-mangostin and exhibited promising IC50 values of 14.1 and 13.5 µg/mL, respectively against DU-145 cell lines. Furthermore, the subject AgNPs showed promising catalytic activity in the reduction of dyes and food colours including Congo red (CR), methylene blue (MB), methyl orange (MO) standard dyes, and zarda yellow (ZY), deep green (DG), and bright red (BR) food dyes. Finding of this study suggests the suitability of the subject AgNPs as promising target in anticancer drug development, and as catalyst in dyes degradation.
Page(s):
274-274
DOI:
DOI not available
Published:
Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
antioxidant
,
Anticancer
,
Dyes
,
AgNPs
,
amangostin