The effects of Acetylsalicylic acid on the pituitary Prolactin of the lizard, Uromastix hardwickii. | [Pakistan Journal of Pharmaceutical Sciences • 2005]

Author(s):

1. Mahmood Ahmad: Department of Physiology, University of Karachi, Karachi, Pakistan

2. Ruqaiya Hasan: Department of Physiology, University of Karachi, Karachi, Pakistan

3. Shama Masroor: Department of Physiology, University of Karachi, Karachi, Pakistan

4. Manroor Ahmad: Department of Physiology, New York Medical College, and Westchester Hospital, Valhalla, New York, U.S.A

5. Anila Qureshi: Department of Physiology, New York Medical College, and Westchester Hospital, Valhalla, New York, U.S.A

Abstract:

This study deals with the intravenous administration of 7mg acetylsalicylic acid (ASA) solution to Uromastix hardwickii for 4 days. It enhances the activity of anterior pituitary lactotrophs, when 0.1 ml of pituitary homogenate of ASA treated was injected hypodermically to crop- sac showed a greater diametric response and increased activity with milk like secretion than that of the injections of 0.1 ml homogenate of control pituitary. The present study indicated that ASA induces hyperprolactinemia.

Page(s): 42-45

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 18, Issue: 3, Year: 2005

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