To compare the efficacy of 35% glycolic acid along with micro-needling versus platelet rich plasma along with micro-needling in treatment of the acne scars | [Journal of Pakistan Association of Dermatologists • 2023]

Author(s):

1. Maida Ulfat: Department of Dermatology, KEMU, Mayo Hospital,Lahore,Pakistan

2. Mah-e-Neema Asghar: Department of Dermatology, KEMU, Mayo Hospital,Lahore,Pakistan

3. Zahra Aooba: Department of Dermatology, KEMU, Mayo Hospital,Lahore,Pakistan

4. Noshi Ilyas: Department of Dermatology, KEMU, Mayo Hospital,Lahore,Pakistan

5. Altaf Hussain: Department of Dermatology, KEMU, Mayo Hospital,Lahore,Pakistan

6. Shahbaz Aman: Department of Dermatology, KEMU, Mayo Hospital,Lahore,Pakistan

Abstract:

Objective To compare the efficacy of 35% glycolic acid combined with micro-needling versus platelet rich plasma combined with micro-needling in the treatment of acne scars. Methods This randomized controlled study was conducted at Department of Dermatology, Mayo Hospital, Lahore from July 16, 2022 to January 15, 2023. 60 patients fulfilling the selection criteria were enrolled. Group A went through micro-needling combined with 35% glycolic acid (containing glycolic acid) and group B went through micro-needling combined with platelet rich plasma. Scars were examined before the first treatment session and at each follow up and scored according to Goodman and Baron's Qualitative Acne Scarring Grading System. Final visit was done after 4 weeks of last session. Both groups were compared for efficacy using Chi-square test taking p-value =0.05 as significant. Results In group-A, 7(23.3%) were males and 23(76.7%) were females, while in group-B, 8(26.7%) were males and 22(73.3%) were females. The mean age of patients in group-A was 23.68±5.03 years and 24.48±4.75 years in group-B. In Micro-needling plus 35% glycolic acid group, 26(86.7%) patients had efficacy of treatment, while in Micro-needling plus PRP group, 19(63.3%) patients had efficacy of treatment (p<0.05). Conclusion Micro-needling combined with 35% glycolic acid is a more effective therapeutic modality than micro-needling combined with PRP.

Page(s): 986-990

DOI: DOI not available

Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 33, Issue: 3, Year: 2023

Keywords:

Platelet rich plasma , eolgtAcne Vulgaris , 35 Glycolic acid , Postacne atrophic scars , Microneedling

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