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A facile one-step synthesis of 2-skatyl benzimidazole and its reactions with gramine and N, N-dimethyl aminopropiophenone hydrochloride.
Author(s)
Izhar H Qureshi Pakistan Council of Scientific & Industrial Research (PCSIR) Laboratories, Karachi, Pakistan
Soofia Shahid Pakistan Council of Scientific & Industrial Research (PCSIR) Laboratories, Karachi, Pakistan
Naheed. Sultana Pakistan Council of Scientific & Industrial Research (PCSIR) Laboratories, Karachi, Pakistan
Abstract
A simple one-step synthesis of 2-skatyl-benzimidazole (I) is described. Reaction of (I) with gramine afforded 1, 2 diskatyl benzimidazole (II) while treatment of (I) with N.N-dimethyl amino-propiophenone hydrochloride furnished 1(-R-benzoyl ethyl)-2-skatyl benzimidazole (III). Compounds (II) and (III) have not been described previously.
Publication Details
Page(s) 11-12
DOI DOI not available
Published Journal: Pakistan Journal of Scientific and Industrial Research, Volume: 22, Issue: 1--2, Year: 1979
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