A Case of Neuromyelitis Optica with Systemic Lupus Erythematosus | Journal of College of Physicians and Surgeons--Pakistan : JCPSP 2022

Author(s)

Waleed Shahzad Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

Haris Majid Rajput Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

Muhammad Hassan Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

Tehmina Inayat Department of Medicine, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

Mazhar Badshah Department of Neurology, Shaheed Zulfiqar Ali Bhutto Medical University, Pakistan Institute of Medical Sciences,Islamabad,Pakistan

Abstract

Neuromyelitis Optica (NMO) is a rare idiopathic autoimmune demyelinating disease of the central nervous system (CNS) having a relapsing course. It consists of optic neuritis, longitudinally extensive transverse myelitis (LETM) which involves 3 or more neighbouring portions of the spine and positive serology for anti-NMO IgG antibodies.NMO is often misdiagnosed as multiple sclerosis (MS). Limited literature about NMO and its association with other systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) is available so far. Here, we present a 21-year girl, previously diagnosed case of SLE seven years back, who su ered attacks of transverse myelitis. She had seropositivity for anti-aquaporin-4 (anti-AQP4) receptor antibody. An accurate clinical diagnosis is important to initiate timely immunosuppressive therapy to prevent disability.

Publication Details

Page(s) 1498-1500

DOI DOI not available

Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 32, Issue: 11, Year: 2022

Keywords

Systemic lupus erythematosus Neuromyelitis optica Transverse myelitis

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