Urease inhibitors and antioxidants from vernonia cinerascens | [Journal of Chemical Society of Pakistan • 2011]

Author(s):

1. Irshad AHMAD: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, PAKISTAN Faculty of Pharmacy, Bahauddin Zakariya University Multan, Pakistan

2. Muhammad ASHRAF: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, PAKISTAN

3. Bashir Ahmad CHAUDHARY: Faculty of Pharmacy, Bahauddin Zakariya University, Multan, PAKISTAN

4. Khalid Hussain JANBAZ: Faculty of Pharmacy, Bahauddin Zakariya University, Multan, PAKISTAN

5. Muhammad UZAIR: Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Pakistan

Abstract:

Eight compounds have been isolated for the first time from Vernonia cinerascens namely, 2-hydroxy-3-methoxy-5-(2-propenyl)-phenol (1), vanillic acid (2), isoferulic acid (3), caffeic acid (4), methyl gallate (5), uridine (6), 3'-methylquercetin (7) and quercetin (8), respectively. Their structures have been elucidated based on EI-MS, HREI-MS, FAB-MS, HRFAB-MS, 1H-, 13C-NMR spectroscopic data and in comparison with the reported data. All these compounds exhibited promising antioxidant and significant urease inhibitory activities.

Page(s): 114-117

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 33, Issue: 1, Year: 2011

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