The effects of brisk walking training on the lipid lipoprotein profile in hypertensive male adults. | [Pakistan Postgraduate Medical Journal • 2004]

Author(s):

1. Muhammad Azhar Mughal: Department of Pharmacology and Therapeutics, Sir Syed College of Medical Sciences for Girls, Karachi, Pakistan

2. Sikander Adil Mughal: Departments of Physiology, Peoples Medical College for Girls, Nawabshah, Pakistan

3. Israr Ahmed Akhund: Departments of Physiology, Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan

4. Ikramdin Ujjan: Department of Pathology, Postgraduate Medical Institute, Lahore, Pakistan

5. Irshad Ali Alvi: Department of Medicine, Peoples Medical College and Hospital, Nawabshah, Pakistan

6. Muhammad Yousuf Memon: Departments of Biochemistry, Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan

7. Ali Akbar Rahu: Departments of Biochemistry, Peoples Medical College for Girls, Nawabshah, Pakistan

Abstract:

High blood pressure is an important cardiovascular risk factor. In Pakistan, hypertension has become a major health problem. A number of risk factors for coronary artery disease are known to be present in hypertensive patients, the most important being hyperlipidemia. The reported data on the effects of aerobic exercise (brisk walking) on blood pressure and lipid-lipoproteins is sparse in our local setup. Several non-pharmacological or lifestyle approaches can reduce blood pressure this needs to be evaluated. Objective: The goal of this trial was to examine the effect of aerobic physical training (brisk walking) in patients with essential hypertension on lipid-lipoprotein levels. Design and Setting: A prospective, single-Centre, non-invasive physical exercise intervention conducted during September 1999 to January 2000. Subject and Methods: Twenty-seven men with established stage 1 or 2 essential hypertension were recruited from Nawabshah, Sindh-Pakistan, with a mean ± SEM age 39.8 ± 0.7 (aged 34 to 48 years); body mass index 23.1 ± 0.3 kg/m2. All consecutive hypertensive patients visiting the clinic were screened and enrolled, if they met the study criteria. All subjects underwent a baseline clinical history investigation, consisted of personal interview, physical examination, and drawing of fasting blood samples to measure levels of plasma lipid concentrations. Serum total triglycerides, total cholesterol and HDL-cholesterol were estimated using enzymatic-colorimetric methods, whereas, LDL-cholesterol concentration was calculated using Friedwald formula. Blood pressure, body weight, lipid and lipoproteins were measured in each patient at the time of enrollment and at 12-week of brisk walking exercise intervention and were followed. The exercise protocol consisted of mild 30 minutes duration for 4 times a week (12-weeks of brisk walking); the fitness of study participants was assessed using cycle ergometer at 50% of maximum oxygen uptake (VO2max) intensity calculated using Karvonen`s formula. Results: This study demonstrated significant reduction of systolic blood pressure (p

Page(s): 60-65

DOI: DOI not available

Published: Journal: Pakistan Postgraduate Medical Journal, Volume: 15, Issue: 2, Year: 2004

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