Author(s):
1. Uzma Akhlaque:
Department of Electrodiagnosis,Armed Forces Institute of Rehabilitation Medicine,
Rawalpindi, Punjab,Pakistan.
2. Saeed Bin Ayaz:
Department of Rehabilitation Medicine, Combined Military Hospital Jhelum, Punjab, Pakistan
Abstract:
Development of acute motor axonal neuropathy (AMAN) in children with acute lymphoblastic leukemia (ALL) is a rare phenomenon and needs to be differentiated from neuropathy induced by chemotherapeutic agents as both require different treatment protocols. The later may warrant adjustments in the chemotherapy regimen. Electrodiagnostic (EDX) studies play the key role in this differentiation. We report here an 11-year-old girl with ALL who presented with signs and symptoms of a rapidly progressive neuropathy diagnosed as AMAN through EDX studies, and achieved a better recovery following timely immunomodulatory therapy, electrical muscle stimulation of the key muscle groups, and therapeutic exercises. The differentiation between AMAN and chemotherapeutics' induced neuropathy through EDX studies is important in children with ALL to initiate timely immunomodulatory therapy for AMAN and avoid unnecessary withdrawal of chemotherapeutic agents.
Page(s):
74-77
DOI:
DOI not available
Published:
Journal: Journal of Postgraduate Medical Institute, Volume: 34, Issue: 1, Year: 2020
Keywords:
GuillainBarre syndrome
,
Acute Lymphoblastic Leukemia
,
Acute motor axonal neuropathy
,
Electro diagnostic studies
References:
References are not available for this document.
Citations
Citations are not available for this document.